Anti-Doping Agency (USADA). It falls under Category S2: Peptide Hormones, Growth Factors, Related Substances, and Mimetics on the WADA Prohibited List, often specified as a "Growth Hormone Releasing Hormone (GHRH) and its analogues" or a "Growth Hormone Secretagogue (GHS)". The ban is due to its potential to unfairly enhance athletic performance by increasing muscle mass, strength, reducing fat, and improving recovery. The prohibition applies regardless of its mechanism of stimulating endogenous GH, as the outcome of artificially elevated GH/IGF-1 is the concern
Meier A, Weidmann P, Glck Z, Keusch G, Grimm M, Minder I et al
This receptor belongs to the family of G-proteincoupled receptors (GPCRs) , which, upon activation, initiate intracellular signaling cascades that lead to GH secretion
Meticulously developed for advanced investigation within endocrine, anti-aging, and metabolic research fields, this molecule is rigorously studied in highly controlled laboratory environments for its profound ability to stimulate endogenous growth hormone (GH) release
This is indicative of modulation or gating of the motivated response for food by systemic signals of energy homeostasis [384]
